GAINEHAIR ManufacturerWockhardt Limited (Derma) GenericMinoxidil Package/sLotion 2 %, Lotion 5 %, About MinoxidilA potassium channel agonist,Direct-Acting Vasodilator, Hair- growth stimulant,In androgenic alopecia. DosageTopical Adult: Apply 1 ml solution on the dry scalp and hair 2 times daily for 4 months or longer Children: contraindicated PregnancyContraindicated. Breast FeedingContraindicated. Old AgeUse with caution above 65 years: contraindicated ChildrenContraindicated NEONATES: contraindicated Mechanism Of ActionMinoxidil works by activating PGHS 1 (prostaglandin endoperoxide synthase-1) which helps promote hair growth. It enhances follicular size and results PharmacoKineticsAbsorption: It is poorly absorbed after topical administration. AdverseEffect1.Headache 2.Dizziness 3.Irritation 4.Itch 5.Contact dermatitis 6.Palpitation 7.Irregular heart beat 8.Nausea 9.Vomiting 10.Diarrhoea 11.Der. SpecialPrecautions1.Renal impairment 2.Hepatic impairment 3.Cardiac impairment 4.Avoid contact with broken area, eye and mucus membrane Indications1. Alopecia areata 2. Androgenic alopecia. StorageStore at room temperature. Protect from heat and light. Keep out of the reach of children. MissedDosageApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose. OverdoseGive supportive measures and symptomatic treatment. Thoroughly wash the hair. In accidental ingestion drug can be removed from the body by inducing emesis or gastric lavage. Absorption of the drug can be reduced by administration of activated charcoal.
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